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KMID : 0363220140520010007
Korean Journal of Dermatology
2014 Volume.52 No. 1 p.7 ~ p.12
Characterization of Two Kinds of Filler for the Formulation
Song Yi-Sub

Kim Hyeong-Mi
Lee Yong-Hee
Son In-Pyeong
Park Kui-Young
Li Kap-Sok
Kim Beom-Joon
Abstract
Background: Hyaluronic acid (HA) is a carbohydrate, occurring naturally throughout the human body. With linear polysaccharide structure, it is (HA) found in soft connective tissues, cartilage and joinfluids. Hyaluronic acid filler is used for treatment of depth of the fold or volume of filler needed and performed for wrinkle improvement and cosmetic. We did property of matter for the Perfectha(R) fillers.

Objective: Our purpose is to describe and comment on our experiences with two kinds of Perfectha(R) fillers.

Methods: We obtained image of the shape of fillers using a folliscope, VC98 and particle size using the Scanning electron microscope (SEM). We tested to make sure that affinity both fillers with water. We mixed the fillers and distilled water. We the PARKER ink added to the mixture. Viscosity and elasticity were measured using a rheometer.

Results: The test revealed that a particle sized Perfectha(R) derm deep is bigger than a Perfectha(R) derm. We were confirmed as hydrophile. While Perfectha(R) derm deep filler has high viscosity and elasticity, Perfectha(R) derm filler has high viscosity only, not elasticity.

Conclusion:Two kinds of Perfectha(R) fillers act as space filler by binding to water and thus keeping the skin wrinkle-free.
KEYWORD
Elasticity, Filler, Hyaluronic acid, Hydrophile, Viscosity
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